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Which statement correctly describes the relationship between Italian city-states and the European Renaissance?

AThe Renaissance began when Catholic leaders in Italian city-states reacted against the Northern European ideas of secularism and humanism.
BThe Renaissance began in Italian city-states, where middle-class citizens grew to challenge the traditional powers of feudal Europe.
CThe Renaissance began in Northern Europe, where men like Johannes Gutenberg made revolutionary discoveries that bankers from Italian city-states profited from.
DThe Renaissance began in remote Germanic villages, where people discovered the ruins of classical civilizations tied to the Italian city-states.