How does replication of the lagging strand of DNA compare with replication of the leading strand?

AThe replication process is identical for both strands.
BOkazaki fragments are made on the lagging strand but not on the leading strand.
CThe leading strand and lagging strand are copied in the same direction.
DDNA ligase works on the leading strand while DNA polymerase works on the lagging strand.

Question

24-12-2016
Biology

Answered

How does replication of the lagging strand of DNA compare with replication of the leading strand?

AThe replication process is identical for both strands.
BOkazaki fragments are made on the lagging strand but not on the leading strand.
CThe leading strand and lagging strand are copied in the same direction.
DDNA ligase works on the leading strand while DNA polymerase works on the lagging strand.

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Answer: The correct answer is- B) Okazaki fragments are made on the lagging strand but not on the leading strand.

DNA replication is a biological process in which two identical replica of DNA are produced from single original DNA molecule through an enzyme called DNA polymerase.

The strands of double helical DNA are first separated ( with the help of helicase enzyme) so that the template DNA strands are exposed. DNA is synthesised in 5' to 3' direction.

Leading strand ( whose template strand is 3' to 5') is synthesized in continuous manner as DNA polymerase moves along the direction of replication folk.

Whereas lagging strand ( whose template strand is 5' to 3') is synthesized in a discontinuous manner as it requires multiple primers to synthesise the DNA. It generates small fragments of DNA called okazaki fragments.