Answer: Option E is the correct answer
Explanation:
T cells are part of the adaptive immune system and have a large repertoire of receptors that allow their activation or inhibition. T lymphocytes or T cells have the ability to recognize and lyse (kill) infected or transformed cells; these transform cells could include cancer or tumor cells. This recognition is due to the contact of the T cell receptors (principally the T cell receptor) with the Major Histocompatibility Complex molecule I (also known as MHC I). When cells are infected or are transformed, the expression of these MHC I molecules are altered, and therefore it is detected by T cells as something “abnormal” and therefore release molecules that cause cell death, such as perforin, granzymes, IFN-γ and the Tumor Necrosis Factor-α. Therefore, T cells can kill cancer or infected cells and interact with MHC-I molecules.
